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z.tavakkol

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= | سيد BIO-SURFACTANT Zahra Tavakkol

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WHAT IS SURFACTANT ? Surfactant :Surface active agent + lower the surface tension between : 1)two liquids 2)liquid and a solid 3)Liquid and air hydrophil hydrophob ON

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Classification hydrophil hydrophob a> OC SS آذآ سکس 2۳ Bee 2۳ 3 ‏سس‎ (1) Classification by structure | (© RCOONa ionic 1 cationic - 6 9 L amphoteric =O) R-NH,*CH,CH,COO ester R-COO(CH,CH,O),H R-COOCH,C(CH,OH), ether R-O(CH,CH,O),H: Perregal anionic *\ nonionic 1 RN CHCR Oe amine R-NQ(CH,CH,O),H 5 ‏(0را یا رز‎ amide RCON{ (cy,CH,0),H algal _—_— R-(OCH,CH,),0S0,Na* nonionic-anionic http:// hosnani.com/ surfactants.php

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ها ‎HLB‏ Solubiizing agents (15-18) Hydrophilic | Detergents (13-15) (water soluble) ‘ow Emutsifying agents (8-16) Wetting and Water 4 ‏ی‎ | spreading agents (7-9) | \wlo Emulsitying agents (3-6) Hydrophobic Antifoaming agents (oil solutie) | 88 https://en.wikipedia.org/ wiki/Hydrophilic- lipophilic balance The hydrophilic-lipophilic balance Griffin’s method.

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Critical micelle concentration Surface tension (mN/m) Biosurfactant concentration (g/L)

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FUNCTION Roll-up Surfactants may act as detergents, wetting agents, emulsifiers, foaming agents, and dispersants. ۶ 5 1 | NS t 422 ‏تا‎ هدس 3 SY ‏کر‎

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Infant respiratory distress syndrome (IRDS) a a ‏و نس‎

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SP-C Structure Jehanmaon, eta, 1994 Biochemicoy 33, 6015 http:// www.t relazioni/

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Bio-surfactant ? surface-active substances synthesized by living cells. Can be made from : plant oil, plant carbohydrate and animal oil

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SS cn ™ BIO-SURFACTANT VS. SU RFACTAN

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4 [BIOTECHNOLOGY - Vol V— Production of Bissutictans -F. Sirs RK Hommel, H-P. Kleber PRODUCTION OF BIOSURFACTANTS, oo Biosurfactant Tension 5 (mN m*) [Cellobioselipids F, Sineriz 5 <1 ‏اه سوم‎ Institute of Microbiology, University of Tucuman- PROIMI, Argentina 1-18 Mannosylerythriol lipids R. K. Hommel 1 Rhamnoselipids Cell Technologie Leipzig Germany 22 Sophoroselipids ‏تون‎ Lo ‏وه ی‎ Institute of Biochemistry, University of Leipzig, Germany mycolates mono | non-ionic 32 3 16 1 non-ionic 36 4 17 1 non-ionic 26 15 1 Lipopeptides licheniformis glucose of non-ionic 27 0.02-10 1 Surfactatin Bacillus subtle 3۹ ef on fonle 2 5 1 Deb, = eell-bound; c.f. = cell-free (extracellular) in dependence on culture conditions Table 1. Some properties of selected biosurfactants from a range of microorganisms.

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HYSIOLOGICAL ROLE OF BIO-SURFACTANT IN MICROORGANISMS * permit microorganisms to grow on water-immiscible substrates * antimicrobial activities towards various micro-organisms * emulsify the hydrocarbon substrate and facilitate its transport into the cells

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FACTORS AFFECTING BIO-SURFACTANT PRODUCTION Carbon sources: Diesel, crude oil, glucose, sucrose, glycerol Nitrogen sources: urea peptone, yeast extract, ammonium sulphate, ammonium nitrate, sodium nitrate, meat extract and malt extracts Environmental factors: temperature, pH, aeration Salt concentration

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TYPES OF BIO-SURFACTANT Biosurfactants are mainly classified according to their chemical structure and their microbial origin. 1)glycolipids, 2)phospholipids, 3)polymeric biosurfactants and lipopeptides (surfactin). Sophorolipids J] sophorose Rhamnolipids [rhamnose Trehaloselipids [trehalose

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* Glycolipids : Rhamnolipids , trehalolipids , sophorolipids 0 Rhamnolipids :

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TYPES OF BIO-SURFACTANT * Glycolipids : Rhamnolipids , Trehalolipids , Sophorolipids 0 Trehalolipid : ° 0 po mycolates group : He Ho Mycobacterium, Ho 2 Rhodococcus, none Arthrobacter, 0 Nocardia 9 Gordonia[8] 6

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TYPES OF BIO-SURFACTANT + Glycolipids : Rhamnolipids , trehalolipids , sophorolipids 0 Sophorolipids : sophorose 0 09 candida and the starmerella ZA

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۱۸0000 8

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| peptide loop of seven amino acids (L-aspartic acid, L-leucine, glutamic acid, L- leucine, L-valine and two D-leucines) TYPES OF BIO-SURFACTANT + Lipopeptides and lipoprote Bacillus subtilis ] Surfactin | hemolytic acti ‎wy‏ جر هه ‎ ‎WARY se hydrophobic fatty acid chain thirteen to fifteen ‎carbons long which allows it to penetrate cellular] membranes. ‎ ‎ ‎ ‎ ‎

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ها TYPES OF ۳ ۲ + Lichenysin Bacillus licheniform. 0 NH ‏جم‎ 0 ‘oh 5 9 ۳ ۴ OX Ho’ Pact HO ‏ی‎ Lichenysin A Surfactin

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۱ APPLICATIONS Biosurfactants have several applications in agriculture, medicine, petroleum and industry. Deepwater Horizon Detergents, Emulsions , Soaps , Paints , Adhesives , Inks , Anti-fogs Biopesticide Agrochemical formulations + Herbicides * Insecticides In medicine : Antimicrobial , Anticancer , Antiviral , gene delivary , drug delivery, Immunological adjuvants food processing industry Application of biosurfactant in petroleum Cosmetics * Shampoos + Toothpastes

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| The overall biosurfactants market is estimated to rise at a compound annual growth rate of 5.60 percent between 2017 and 2022 * Sophorolipid is the most important type of the overall biosurfactants market * Detergents is the most important application segment of the overall biosurfactants market + Europe (EU) to be the biggest biosurfactants market during the outlook period https://www.reportlinker.com/p05253739/Biosurfactants-Market-by-Type- Lipopeptides-Phospholipids-Polymeric-Biosurfactants-Application-And-Region- Global-Forecast-to.html

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م۳۳ << HOME ABOUT AGAE APPLICATIONS —RE5.——-RNAMNOLIDGISHURFACTANT ‏هم‎ ‎ORDER —_MAYLU PRODUCTS NTACT US

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۱ REFERENCES + Franzetti, A., Gandolfi, |., Bestetti, G., Smyth, T. J. P. and Banat, |. M. (2010), Production and applications of trehalose lipid biosurfactants. Eur. J. Lipid Sci. Technol., 112: 617-627. doi:10.1002/ejlt.200900162 + Santos DKF, Rufino RD, Luna JM, Santos VA, Sarubbo LA. Biosurfactants: Multifunctional Biomolecules of the 21st Century. Taubert A, ed. International Journal of Molecular Sciences. 2016;17(3):401. doi:10.3390/ijms17030401. * Fakruddin Md (2012) Biosurfactant: Production and Application. J Pet Environ Biotechnol 3:124. doi:10.4172/2157-7463.1000124

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۳ | یت Thanks for your attention

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