کومارین ها به زبان انگلیسی

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What is ?coumari, per derivates ‏اه‎ 8 -pyrone 

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Coumarin is a natural product well known for ‏ككل‎ 0۱6۵5۵۱۲ ۷۵۱۱۱۱۱۵- like odor. Coumarins owe their class name to ۳ ۱ ۱۷۵۲۳۱۵۵۱۷۱۵۲ ۱۵۱۵ ۴ the tonka bean (Dipteryx odorata Willd, Fabaceae), from which coumarin, it was 

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Coumarins along with its derivative occurs : abundantly in plant families such as ‎a ee‏ ا د ‎asteraceae wenbellifer rutaceae‏ ‎a‏ 

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solanaceae — orchidacea @ 

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‘Biosynthesis of coumarin a S000 ‏مس‎ ‎: ‎0 i Sy Sy 0008 ۳ CCL = cr 5 26 ‘O-glucose "OH o-glucose ۱ (©-coumarie acid beta-o-glucose O-coumaricacid 0 2 Coumarin Umbellferone 

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Coumarins play role in plant >> — and are biosynthesized “de novo” in stress conditions as phytoalexins. In low concentration they ‏ها‎ ‎with plant growth :promoting 

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Coumarins occur in plants in free -from or as glycosides Aglycone are soluble in petrol, benzene, ether, chloroform, diethylether, alcohol (nonpolar solvent) are soluble in water and alcohols (polar solvent) 

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:Classification of coumarins 5 Simple coumarins Furanocoumarins Pyranocoumarins Benzocoumarins 

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ارآ ۲۳۱/۱299 

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FURANOCOUMARI 7۸۵ Furanocoumarins are formed in ‏اوافل ی یا لنت لحن‎ condensation in _ position (psoralen-derivatives) or ۰ .(angelicin-derivatives) ST a idee miracle ide) .these rings 

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Xanthyleti n :PYRANOCOUMARINS Pyranocoumarins are result of condensation of coumarin with 2,2- dimethylpyrane in positions ; ;or and may have Te) SA a ieee MTN ae) i rings 

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BENZOCOUMARIN AS Benzocoumarins containing benzyl .condensed with coumarin in 3,4 position 

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coumarins occur at the highest levels in the fruits, :followed by the roots, stems and leaves ge ته Strawherr 

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licorice 6 هو( 

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Sesquiterpene 8 ‘coumarins Sesquiterpene coumarins constitute an interesting ‎a]‏ اع ا لللنيلعية ‎They are a group of molecules whose structures are basedona == _ moiety linked through eitheran _ linkage with Bie envoroxy ‏ها‎ 0 

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gumosin SET) 

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Part of coumarin in De ee ‘coumarins 000 01500178 - fo fab E le [Ty] 

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Sesquiterpene umbelliferyl tethers _ Beate! ‏داتسا‎ 52۳2 12 « conferol acetate 

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»poletin-derived sesquiterpene ms scopofarnol scopodrimol ‏وا‎ Tele re Titel 

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USES OF 7:COUMARINS As a food additive and ingredient in دلییزازوت: ۱ 

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WARFARI 5 لع5نا ‎erate‏ لا ‎santicoagulant‏ 

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Detection of Coumarin in Plant 5 ‘Extracts Coumarins can be detected in plant extract by means MY ‏أده امعتصضعطء‎ Take 0.01 g of the extract in a test tube and moisten SMe ella ۲ The mouth of the tube is then covered with filter Paper treated with = solution. The test tube em ‏دیا کته‎ M ‏رعغدقتنا ومتلامط دا دع تامام‎ Lite ‏معط‎ ‎the filter paper is removed and examined under | Aight Yellow-green fluorescence indicates the presence of Rotor Tait) 

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: 26661707 0۴ 5 ‎fluorescence quenching‏ را ل انا 5 اه الة 01. ‎UV-365 nm run intense blue or blue-green -fluorescence (simple coumarins) ‎Yellow, brown, blue or blue-green -fluorescence (furano and pyranocoumarins) 

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‘Detection of Coumarin The fluorescence of the coumarins are intensified by spraying with 5%- 1096 2 § (04. Concentrated ‎has the same‏ ل ‎.effect‏ 

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Pharmacological Activity of 5 7Coumarins Anticoagulant Estrogenic Antimicrobial Vasodilatory Anticanser Rye FT} Hypnotic Analgesic ۸2۸7۴۵۸9۵1 

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Refernce ۳ 5 Poumale H.M., Hamm R., Zang Y., Shiono Y., kuete., "8 (eT Eee eM © ‏5غ واط اهدل أ0ع1! وءذاخ ددره؟1 001105م0111‎ 0+ Africa", Medicinal Plant Researchin Africa Elsevier Inc (2013) 261-300 Wagner H., Bladt S., "Plant Drug Analysis: Coumarin Drugs", Springer Berlin .Heidelberg (1996) 125-147 Gliszczynska A., Brodelius P.E., "Sesquiterpe: Phytochemistry Review 11 (2012) 77-96 

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