مراقبت‌های بهداشتیپزشکی و سلامتسایرتحقیق و پژوهشطب سنتی

Herbal drugs/ Pharmaceuticals – Problems and Prognosis

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Herbal drugs/ Pharmaceuticals - Problems aed rognosis Oreo, Dated Bokmicd Research ‏ها‎ ‏سرا‎ ۰

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5trillion$ /\ Herbal drugs | 62 Growing popdidhep $ Business standar ai

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= Drugs Required for masses.. ccessible ffordable ssured safety

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Do they fulfill the requirements

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۱88۰ [06 7 About 70% Indian population (60-70 crore) depends on alternative system of WHO

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= Affordable ? Herbal drugs are cheaper than generic drugs !!??

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Herbal drugs have been used in India for more than —— 4000 years.

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a Allopathy or Modern NBRI Medicine Ckxoorized disviplice Qursued by wot (inPhueaed ood s7 voted ‘Literate’) fo Veda ood, i Wester countries Qucked by teckurloyicd adveaces - wesicaioas Oued oo soudd sviewihic ‏موجمج‎ — experiwectal puidew ‏اوه بو‎ ‎Dkus, Orders Oediiug is wa evidewe-bosed,‏ سس ‎techuv-suwuy svieuce thot spews to provide uliczate‏ ‎pure to sick pote‏ ‎ ‎

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Allopathy or Modern Medicine Phe teeukoed is oPtea sywpiowaiic, vost, vot oP reuck oP wost ia develppicg pouties @xvept Por icPeviive poolowes, we ‏مهو ول‎ wwuk to oPPer except politic ‎oP Ohrvuic biPestpte Disorders lke‏ مهب ‎heeds the Oiseuse (syxepiowstir) ood oot the poticot‏ ‎‘oe awh’ (Wolsic approach)‏ ‎ ‎ ‎NBR ‎

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NBRI Therapeutic Objective Dee ‏من‎ yoo! oP every physica is to “COREG” ‏.حول سا‎ Woes @llopothy achieved this yoo Por ‏ماه له‎ Ov; xcept Por inPeciive poholoyies, we do at uchieve CORE Oost oPtec the ‏امسر و امه‎ od Pottaive. CPPRecive & © ‏عله‎ Oedicine

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N8R| Drug Discovery - problems his wwtorivusly inePPiciest Ove fo hooded thousand or wore cowpourds wil ecter the worket usu drug @honve woiors kwe OO interest io higher plots extracts Por soreruiay Por bivlogical untiviy 4a DBPROLERD etkaowediod reports Por OP, OOO ppevies (O.C% vf all past spevies) ure there; Ou GO% of these spevies have vever beru exaviced biologically or ‏تلد اجات‎ OP these PP% ore used feo women whirl parcels their ‏مسا‎ use

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NBRI Golden triangle Traditional medici: Modern Modern medicine science Thus making cheaper affordable and safe medicine Mashelkar

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UFcamples of some important plant derived drugs | ‏مه‎ (Pht Opwoter Bord ‏سید‎ (۵ — ‏تست‎ SS ‏مت طلست ساسم‎ ‏ممصم سيو ره عد بوه‎ ‏سیم‎ recone ‏تهت محم عسمنه‎ a ‏چیه‎ ‏تفس سمجین‎ OF ‏عه م0‎ ‏سره تفه‎ ‏سین‎ — ‏تور بیج‎ ‏هه شمه سسالنته تم‎ ‏ساس جح‎ ‏موه مه سیم‎ eae in ‏تسس یه‎ ‏مسب طلست سس‎ ‏ام سر مس مسسممم مضعق سا سب مسب‎ ‏تا له ممصا ,صصص‎ ‏يسود بس .عجر سحو مسا‎ Contd

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ples of some important plant derived drugs (Contd..) که موسر سم سورد Poh (nan, Orne ‏اجه‎ ] (Onporenral & Oarsxred) ‏سوه سره‎

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Traditional medicine Historical background Caniest nevorded use oP a wedivicdl phorot has beeo weutivoed io ‘Rigveda’ poe weotivoed fo the wodern texts is that oF the kerb wrtted “Ou kucay” a spevies oP Ephedra used ‏وآ انلس‎ Chica Por puer GOOO pews Chacko was used by locd souk Owenoon tribes ‏حصا‎ ‎bePore bePore the isvlatica oP quiciae Por treatioy cvotaria Gourve oP uspiria (Gui oP Picicaks) wes used as pois killer Por iro teoe beP one betay ‏اعد‎ NBRI

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NBRI Traditional medicines QDidkdthe oP dO pestury, OO% vf al wedivices were kerbal Even tty CS% vP drugs ure derived Proc phrat SUE Oost oP these ‏الما ما موه رم‎ fead, Pots ‏,اه لالب‎ Gowe oP ese sl ood wot substiued despite he

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NBRI Revival of herbal medicine widespread belie? thot ‘Greed wedicioe is Keuthier thos sythetic products feadiag 17 rapid spurt oP decoad Por Keath products the herbal tea, yoseog ord suck products oP ‏یی الم‎ Go ropid — se oP herbdl products ore stacgericey (OO bitios ‏و وا‎ peor. اوه و لوب صووب لا مهو رال ‎Tada oad‏ ۳ او ‎workieg oot‏ OWN kas set up COO ‏وی‎ cad worhicg oa Gt. doko’ wort wad Birgh bilpbo

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Drug development based on traditiona NBRI pad 6001061116606 6168 01 0 108 species authentication Stier ‏ات‎ atc Biological iy T, Analytical GES eee ‏اه‎ Serene 517 ‘Active Compound(s) Character} قافتا یوت ا نا 1. Pharmatology ‎Toxicity‏ ,2 3 د ‎Clinical‏ .3 بویت ‎Pharmacokinetics/ Pharmacology‏ ‎PharmacodyreibeicBlant 4‏ ‎Production 00101۵ ‏نا‎ ‎Marketing

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۱۱8۸۱ ۳۵۷۲۵۲:۵6 7 Okt is nequiced is “OnieniPic evidewe” ‎Por‏ مص بح جما جریا ‎und suPety‏ رز( ‎Goreesicy bused oo ‏مه ام ماه‎ ethacbotacicat feod as choues oF hittogy the target is wore ‎

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| PHARMACOLOGICAL SCREENING OF TRIBAL REMEDIES مالس ] جد نصح ج ب ‎ee paras‏ م سا ‎aoe | mp | Bae‏ 1 و ‎com] es Tew]‏ عع ]| ‎Se eee‏ ‎ey [pas] + = fe‏ ‎FS‏ | [ تس ‎ ]‏ [ مده ‏تا هم ‏سمدم |[ .د ] هه [ عدم ‎ ‎ ‎ ‎ ‎ ‎۱ ۳ 5 ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎

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NBRI System biology ۳۸۲۳۲ The health triangle. The survival potential of all living systems, H, is expressed in the health triangle, structured with life's common denominator: Intelligence, Energy and Groanization.

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NBRI Synergy Oost oP the ePRevive phutowedictae fo worket ore os whole extracts oF phorets Crovtticaers believe tha ‏او موادت مرو‎ the powpourts oF fodivicual or wixture DP herbs ure a vital part oP therapeutic ePPicap Qevkudisw oP unticd oP weep phyiowediciae is still ‎where total‏ مها ‎sever‏ و و مه متا ‎] shows better uvivity tho oo ecuoedt dose vp — tovkited powpournd ‎vhewicd ord phocwurvlodiod evideure to dewoustrote ‎voudhosively the pouvept oP syoerdisw ‎

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NBRI Multi-target approach Cowbicativas oP kerbs are word ond ure based pu ewpircd pbservetiod ond ‏و لصو رو‎ ‏ام نموم‎ these herbd vowbicativas wuy ut be targeted to a reuniives urisiagy out oP these hove to be checked Bore cowie ut With the chug

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Multiple Targets Need A Combo v Cartilage Plant A 2» Inflammation Plant B _+ Oxidative Plant ‏حع‎ =——— stress Osteoporosis tee A Anabolic ant CNS Plant F - Immunomodula ۱۵۱۱ ۲۰ ۲. ۵ PlantH.-— Antistress Activity Matrix: Systems-Biology A 11

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2007111312 ام ۱۱8۶۱ 9 ام اطع ‎up thie‏ ‎(POR)‏ تیه رت عصمد) شاه رح ص( تساه ‎Werb-Onag‏ Doxiviy oF the isvloted iocrechouts Dndiicod process (Skodbac)

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a Traditional Medicine: Threats oor posiicsiog ooo ofobal bevel Seon by the <fobdl sviedtiPic ‏ناد صمت‎ ‏سول‎ ‏عمجم شوه صهسصواام()‎

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Traditional medicine: Future ون Innovative, Effective and Aggressive use of Emerging Technologies without Compromising the Basic Principles will be the main key towards the bright future

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Selection of potential plants Activity guided isolation of active ‘copounds cui Discovery 1 0 ۲ مي" Toxicity, ‘Standardization of the Formulation and Doasge studies Phar stuides formulation(s)

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