صفحه 1:
صفحه 2:
An Evidence-Based Approach to
TCM Patient Class Definition
and Differentiation
صفحه 3:
TCM is Worthy of Research
© تا ان تم (TOO) is koportc to the Ohare people.
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۳ edt core
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2 ۳۵96 له چم PO% ۵ اس یه
صفحه 4:
Spectrum of TCM Research
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ty 1 a 1 یلسع
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عام .بعصو ,م2 ,5( ف“
صفحه 5:
Spectrum of TCM Research
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صفحه 6:
Spectrum of TCM Research
اس
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صفحه 7:
Spectrum of TCM Research
ما یی ۰
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صفحه 8:
Spectrum of TCM Research
اس
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تجوت برا ديدص ماس
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صفحه 9:
Pag 9
Wesiers Dedoie (Orders Biowediod Dedcice ) و
Bianco body: 8 wackior wih dPPeredt pots, viewed of dPPeret levels! acaicwic,
bockewicd, تا
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Osewe: Oishorwvay ©
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ام بلج لا موی oF the مسو) ۶
صفحه 10:
Pap 1D
Patient Classes
© Cok Oodera Oediice ood TOO divide putieats toto classes
ای و ما و و
Stace ۵ روط تمه موه هم و ون ۲
Oley defied ©
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مر مک ز(مسلمو) موجه مهن وا لموممپون ۴
Wot det) defied
OP Perrataizg heavy toPecred by abject ©
صفحه 11:
Data-Driven Research on Syndrome |
Differentiation
00
© Labeled و لو تالا سای ,كعات 6 موم نم experts
© Proves quenitaive acr@ortzaiva of experts’ karw-hows
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۱0۳۵ :قطقةانقة ظاتنائة قز" ةق وی اس ساب
صفحه 12:
Pap ©
Our Objective
اه by لاه ارات مخ مره ور ما و ©
اه بو مومس مرول و مره بر و ماه ون و
cue puna.
صفحه 13:
Pap 09
له
Grotstica valdaica oP POO postukates:
توالت CProvidery evidewse Por POO potieat class dePiciicc ced
0
صفحه 14:
TCM Postulates
© POO her poottates to exp om و ار
ر راطع بو ولج ما ts the boasts oF ol voc; tothe body. بر ول
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nnd ook knobs ann back,
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صفحه 15:
Pap 0S
Research on ectivity 0: M
© Por wre tem SO pews, reseurchers have ted to show trot
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hoborciory tests, (reveal yeuetc weed ov)
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appears امد وب و
صفحه 16:
© جوم
0/1 5771101011165 ۸16 1
:نوس ۲۳۵۵
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هنم امین کمن نوی اما میا ماو ©
صفحه 17:
Collective Cognition
Sow del coarepts suck ما مره اه betes?
© مین Crow correhiva betwers observed variable.
© Low tb we possibly prove tiv?
BB Lene Priaciple applet hieracive dew...
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You dP | رح جمومره لامن جن یمرن ۶
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With Patents <
مد
صفحه 18:
© ممم
1011 0
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نع
Data On
‘Symptoms
|
atistical Va
Match?
Tom سر
Theories|
NX
Ancient
Times
Experiences
With Patients
صفحه 19:
Data Analysis Tool
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یت ها bene ar bss
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P(e|va), PAVE), PREVA)... مس م مح م لم
صفحه 20:
Data Analysis Tool
ter wodels: Orterxvice ول مورا
Qucober oF hateat vortables:
rack bateot variable اه راون
Oodel Gtructure
Ovudtioaal probably dotruioas
صفحه 21:
Pap 0
Data Analysis Tool
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صفحه 22:
Pap 2
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صفحه 23:
تا ول وا یاه 2و7
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صفحه 24:
\ —— Y4: cold limbs
GZ — Yz cold lumbus and back
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3
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صفحه 25:
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Postulates
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POO
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Good Match
صفحه 26:
Match between Model and TCM
Postulates
— Model 294
ZINN
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صفحه 27:
oliguresis 34 سم
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صفحه 28:
صفحه 29:
Pap BO
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امین و
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صفحه 30:
Pop OD
Value of Work In View O
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صفحه 31:
Value of Work in View of =
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صفحه 32:
له
Gratstcd vokdaica of POO postulates
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0
صفحه 33:
Pap 99
ما و سوم سین و
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اوه امه اوه ۳
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صفحه 34:
Pape OF
The Idea
erates supple Devers wedone deree O Prow TOO perspevive و
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TCM Theary: Syndrome. Z® 9
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me Class 2: 3
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صفحه 35:
Cluster Analysis
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صفحه 36:
Pap 99
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صفحه 37:
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صفحه 38:
Pap 90
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صفحه 39:
Pap 99
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صفحه 40:
مش وشات اجلعج(1)
اون له( / Observed ©
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vores ]
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صفحه 41:
Poe PC
ry mouth anc throat
headacne
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lstontion ones &nib-sie
thet wth desire to drink
enon
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feeling of lump in teat Se eas
awake early sleep again
‘requent urinaton
كعمو كاملا جه مادم
#مطاهمة امه مقو تاوما
‘constipation istentionin boas
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somnolence couded hae
baling heat
heat in palms & soles
palpttions
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fattongue
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pale white tongue eeling of suffocation
saison tongue
كه - > فك هاون
صفحه 42:
|__ Partition given by Y15_| ~
Partition given by Y15
Probability distrioution of symptom
varablesin the two clusters
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صفحه 43:
Pap PO
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صفحه 44:
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صفحه 45:
Pape PS
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صفحه 46:
Pap PO
Concluding Remarks
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صفحه 47:
eee
‘OPEN @ ACCESS Freely available online PLoS one
Visualization of Pairwise and Multilocus Linkage
Disequilibrium Structure Using Latent Forests
Raphaél Mourad’, Christine Sinoquet™, Christian Dina”, Philippe Leray"
1 UNS, UMA Gs 621, Ene Poytectnigue de FUnivesité de Nantes BP 5050, Nantes France, 2UNA, UMR CNRS 6241, Universite de Nantes BF92206, Nantes France,
Binsteut cu Thorax, UR INSERM 915, BP 70721, Nantes, France
Abstract
Linkage disequilibrium study tepresents a major issue in statistical genetics as it plays a fundamental role in gene mapping
and helps us to learn more about human history, The linkage disequilibrium complex structure makes its exploratory data
analysis essential yet challenging. Visualization methods, such as the triangular heat map implemented in Haploview,
[provide simple and useful tools to help understand complex genetic patterns, but remain insufficient to fully describe them.
Probabilistic graphical models have been widely recognized as a powerful formalism allowing a concise and accurate
modeling of dependences between variables. In this paper, we propose a method for short-range, long-range and
صفحه 48:
Figure 1. Comparison of linkage disequilibrium visualization methods applied tothe Daly etal
Mourad R, Sinoquet, Dina G, Leray P (2011) Visualization ofPairvige and Multlocus Linkage DisequlllviumStuctue Using Latent
Forests. PLoS ONE 6(12): 62720. doi10.137 tjoumal pone.0027320,
اا plosone ornlarlefnfe:de/10.137 Viournal pone 0027320
PLoS one
صفحه 49: