bacillous

bacillous

اسلاید 1: Foundations in Microbiology Sixth EditionChapter 19The Gram-Positive Bacilli of Medical ImportanceLecture PowerPoint to accompanyTalaroCopyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display.

اسلاید 2: 2Medically Important Gram-Positive BacilliThree general groups:Endospore-formers Bacillus, ClostridiumNon-endospore-formers Listeria, ErysipelothrixIrregular shaped and staining properties Corynebacterium, Proprionibacterium, Mycobacterium, Actinomyces, Nocardia

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اسلاید 4: 4Spore-forming BacilliGenus BacillusGenus Clostridium

اسلاید 5: 5General Characteristics of the Genus Bacillus Gram-positive, endospore-forming, motile rodsMostly saprobicAerobic and catalase positiveVersatile in degrading complex macromoleculesSource of antibioticsPrimary habitat is soil2 species of medical importance:Bacillus anthracisBacillus cereus

اسلاید 6: 6Bacillus anthracisLarge, block-shaped rodsCentral spores that develop under all conditions except in the living bodyVirulence factors – polypeptide capsule and exotoxins3 types of anthrax:cutaneous – spores enter through skin, black sore- eschar; least dangerouspulmonary –inhalation of sporesgastrointestinal – ingested spores

اسلاید 7: 7Control and TreatmentTreated with penicillin, tetracycline, or ciprofloxacinVaccines live spores and toxoid to protect livestockpurified toxoid; for high risk occupations and military personnel; toxoid 6X over 1.5 years; annual boosters

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اسلاید 9: 9Bacillus cereusCommon airborne and dustborne; usual methods of disinfection and antisepsis are ineffectiveGrows in foods, spores survive cooking and reheatingIngestion of toxin-containing food causes nausea, vomiting, abdominal cramps and diarrhea; 24 hour durationNo treatmentIncreasingly reported in immunosuppressed

اسلاید 10: 10The Genus ClostridiumGram-positive, spore-forming rodsAnaerobic and catalase negative120 speciesOval or spherical spores produced only under anaerobic conditionsSynthesize organic acids, alcohols, and exotoxinsCause wound infections, tissue infections, and food intoxications

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