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European Congress of Homeopathy — May 18-21, 2011, Riga, Latvia Orofacial Neuralgia-Clinical cases > Homeopathy Treatment - local immunity stimulation Aphrodite Chatzimanuil DDS President of Hellenic Classical Homeopathic Dental Association, NHS Greece Mighalakis Michail. DDS, MSc. Specialized in Oral Radiology Member HCHBA,EADMFR, scientific commi

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© 22% of the U.S. population have orofacial pain incidence on more than 1 occasion in a 6-month period.1 © However, the etiology of pain for countless patients who have chronic orofacial pain disorders is unknown. © Although pain involving the teeth and the periodontium is the most common presenting concern in dental practice, other nonodontogenic causes of orofacial pain must be considered in the differential diagnostic process. Treatment Dilemmas are not rare for both physician and the practicing dentist since © Trigeminal neuralgia mimicks odontogenic pain.2,3 Many acute, chronic, and recurrent painful maladies manifest in the orofacial region.

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79 TN = douloureux 5 © Pain distribution is unilateral. — © Typically radiating along maxillary (V2),mandibular (V1) branche © Rarely both L GR sides r affected © FQ International 155cases/million © 2:3 ratio male/female ۱ \ © Observed >5th decade © DD: multiple sclerosis, TMJ syndrome, post-herpetic neuralgia, Atypical facial pain, glossopharyngeal neuralgia, aneurysms, tumors, Compression of trigeminal roots, chronic meningeal inflammation, Dental problems.. © Signs of neurologic abnormality exclude the idiopathic diagnosis. © Mechanism of pain production remains controversial. fore eet)

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١ “Ist case 9 80 years old-H:1,67, W: 72 kg Proceded with chronic complain of facial painteft{Aphrodite chatzimanuil) -Diagnosed wiyh TN at 1997 NHS Greece, on medication since (Tegretol/200mg 1x3/day and then 3x3 for 6months) -Medical anamnesis: 2 birth deliveries. ۰1979 Removal of phalopian tube due to inflammation -2002: Knee surgery (pnén pnvioKkov) trigeminal pain began at 1997. as mild irritation that were intensified in time. -edentulous

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0 9 “with chronic complain of facial-pain left (Aphrodite 8coutziwianuhe seeks homeopathy. Patient description: Like a penetration of needle that electric current was going through ‘Couldn't eat or speak«Acv pnopovea va paw, Sev propotoa va UAT ow». Antensity was greater in the morning, ameliorated when chewing hard (4). Sleeps on side - desires order and quiet (3), Mild personality, withstands pain, patient and consistent personality “Desires to be in open space (amel) (2) Sensitive to wind currents (Agr). Des: pasta (3) sweet (2) -Avers: Vegies (3) anxious about kids, uncomfort in narrow places clystofobia

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۳ tially took constitutionally remedy Magnesia Phosp. 1Mx10, Follow up ,Feb 2009 Magnesia Phosp. 1Mx4, follow up ameliorated other pathology -08/2007: prescribed with Magn. Phosporica 1Mx10 days. Pain ameliorated gradually to complete within a period of a month. -02/2009: recurrence of pain with less intensity, time duration & intervals. prescribed with Magn.Phosporica 1M x4days. -2009: knee arthitis (Tevixy 12000171 vyetac: KAAH) °1/2011 no complaint reported, knee irritations ameliorated as well. -Didn’t want to speak about it.. again

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© Neuropathic orofacial pain, which is pain initiated or caused by a primary lesion or dysfunction in the nervous system, is relatively common. It is diagnosed in approximately 25% to 30% of patients presenting in a tertiary care University-based Facial Pain Center.2 © using MRI&MRA (angiography to show compression of V n. close to brain stem) routine imaging © Odontogenic orofacial pain mimic TN thus treated as idiopathic due to incomplete diagnosis “nonodontogenic toothache-neuralgia ©The key symptoms of nonodontogenic toothache are as follows:4 spontaneous multiple toothaches; inadequate local dental cause for the pain; stimulating, burning, nonpulsatile toothaches; constant, unremitting, nonvariable toothaches; persistent, recurrent toothaches; local anesthetic blocking of the offending tooth does not eliminate the pain; failure of the toothache to respond to reasonable dental therapy.4

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"2۳0 256 9 74۷/65۲5۵۱۵ ۲:1,69, W: 58 kg Proceded with chronic complain of facial pain right side (Michalakis michail) ® Diagnosed TN in France at 1996 and treated homeopathic with aconite at 1998 © but pain recurrent at 2006( received several remedies ) at 2007 finally Sepia ameliorated symptoms. ® since 2008 on T4

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© 2009 used cortisol-antidote. © 11-2010 in radiology exam appeared dentoalveolar pathology in proximity to 3rd brance of V n. Referred to endondic-specialist © 27 feb completed root canal at tooth 46....(notes...) © Diagnostic observations in several homeopathic cases. Understanding dental pulp pathology will clear out to the prescriber the necessity for diagnosis throughout such cases.

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23-11-2010 Ms MyA-M Following a radiology exam appears to have cystic formation at the root apex of: ‘Tooth 47 largeS. well organized (possible granuloma). (Marked A1) In Tooth No 46 the formation appears to be distal ( marked A2) in the intermediate space-bone of 46-47 applying pressure to the inferior alveolar canal & passing through nerve. (marked as Alv.n) A dental CT for this area is required if pain pathology reappear... 19-1-2011 0 tévoc EeKtvovgEe ané to A 2 (46) oto péonua pe avtidpaon otHy Enixpovon, SvoKoria Katdnoons, oteyvavet o Acids. A) Ref : yta evbobovtia

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Although the etiology and pathophysiology of odontogenic pain is well known (ie, bacteria-induced destruction of tooth structure and subsequent activation of tooth nociceptors), mechanisms underlying trigeminal neuralgia are less

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Trigeminal neuralgia mimicks odontogenic pain ‏یی‎ ‎trigeminal neuropathic pain may exist in many forms and may easily be mistaken to represent one of odontogenic source. Ladies >5th decade are frequent candidates. © The pitfall for the practicing dentist is to focus on the odontogenic pain component,while the physician focuses on the trigeminal neuropathic pain component. °Failure to identify the source of the patient’s entire problem may lead to erroneous and ineffective treatment. ©Therefore, it is important to consider all sources of pain in trying to delineate the etiology and ultimately recommend treatment.

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© Optimum management can only be achieved by determining an accurate complete Diagnosis_ identifying all of the factors associated with the underlying pathology on a case-specific basis. Untreated inflammatory process in the jaws can be harmful in a systemic way, shadowed with a latent period of time.

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ل 86۲۲6۲6۲6 © 1. Lipton JA, Ship JA, Larach-Robinson D: Estimated prevalence and distribution of reported orofacial pain in theUnited States. J Am Dent Assoc 124:115-121, 1993 2. Toothache or Trigeminal Neuralgia: Treatment Dilemmas Christopher J. Spencer, John K. Neubert, Henry Gremillion, Joanna M. Zakrzewska,and Richard Ohrbach The Journal of Pain, Vol 9, No 9 (September), 2008: pp 767-770 19. Gremillion HA: Neuropathic orofacial pain: proposed mechanisms, diagnosis, and treatment considerations. Dent Clin North Am 51:209-224, 2007 3. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995 Jul;80(1):96-100. ‘Trigeminal neuralgia mimicking odontogenic pain. A report of two cases. Law AS, Lilly JP. Department of Endodontics, University of lowa College of Dentistry, Iowa City, USA. © 4. Tex Dent J. 2000 Jul;117(7):64-74.Nonodontogenic toothache.Okeson JP. Orafacial Pain Center, University of Kentucky, College of Dentistry, USA

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Conditions representative of neuropathic orofacial pain are postherpetic neuralgia, trigeminal neuralgia, traumainduced neuropathy, atypical odontalgia / nonodontogenic toothache, idiopathic oral burning, and Complex Regional Pain Syndrome (CRPS), In some instances, diagnosis can be difficult, as neuropathic orofacial pain is associated with significant interpatient variability regarding presentation and response to treatment. Additionally, neuropathic pain conditions are frequently associated with qualities that the patient is not familiar thus making it difficult for the patient to communicate their pain experience. ‘Typical descriptors used by patients include stabbing, burning, electric-like, and/or sharp, with numbness or tingling projected to a cutaneous area. 15,16 However, aching pain does not preclude the possibility of a neuropathic basis for the patient's pain. clinician must decide whether the 2 pain complaints (tooth vs neuropathic pain) are related or are merely coincidental. Such co morbid conditions may result in diagnostic confusion and a perpetuation of the patient’s pain condition. ‘Many acute, chronic, and recurrent painful maladies manifest in the orofacial region. Lipton et al 11 reported that 22% of the U.S. population have orofacial pain on more than 1 occasion in a 6-month period.1

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‘However, the etiology of pain for countless patients who have chronic orofacial pain disorders is unknown. * patients may not recognize an injury or serendipitously report having a relatively minor dental procedure (eg, restoration or root canal) completed at the time of pain onset. ‘Although pain involving the teeth and the periodontium is the most common presenting concern in dental practice, other nonodontogenic causes of orofacial pain must be considered in the differential diagnostic process.

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*Neuropathic orofacial pain, which is pain initiated or caused by a primary lesion or dysfunction in the nervous system, is relatively common. It is diagnosed in approximately 25% to 30% of patients presenting in a tertiary care University- based Facial Pain Center.

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