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www.tabaye.ir
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.. 02۷6۳۷۱6۷۷ 0۴ (۵6 ۲
state of the research in
_ Homeopathy
Dr Alexander Tournier
BSc Cantab PhD LCHE RSHom
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صفحه 3:
Aims
® To show that science and
homeopathy are indeed
compatible
® To present evidence coming from
different fields of science
°© To present Homeopathy Research
Institute
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۲
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Scientific discovery
_. process
1 Observation
Sh,
Experimentation
—_=_
Theories
هل
Understanding v 8
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Unscientific
argumentation
“Homeopathy does not work ...
... because it cannot
work”
is not scientific,
as it is not grounded in observation
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صفحه 7:
Science of homeopathy
Hahnemann built homeopathy
following a rigorous scientific
approach:
© Experimentation
Provings
Clinical experience
®©Theories and concepts
Law of similars
> Principle of dilution
Concept of the vital force LH] 2|
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Different scientific
. approaches
اسب 000 ان ام
2 _
ووه مه
تا ال
‘Dricks oP ePPicaay مس هس۳۳
هل =
(BPRevivecrss to practise 9۳۲ موی ۲اه رسمب
سس كك Gener
مه QOevkouisw oP وی
etd DDO Ded Rew Det QOD? A?) ? | مامت ما لول
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Homeopathy: a new science
Number of scientific publications over the last 20 year
اقا اسهم
a Review Astle
شاك »اديه سه
00
+ Case Report
See
2005 2005 3004 2003 2002 3001 2000 1009 1998 1997 1995 1995 1004 1903 1092 1991 1980 1680 كوو 1087
Adhami H.R. , S.Shamloo D., Mesgarpour B., H.Tehrani S.A.
“The trend of homeopathic articles indexed in pubmed and ISI” LMHI 20
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Scientific evidence in
Homeopathy
© Materials sciences
© Molecular and cellular systems
® Animal studies
® Human studies
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Evidence from Material
Sciences
© NMR evidence (5/5 Hi-Qt* pub) v
® Low temp thermoluminescence {
® Raman and UV-Vis Spectroscopy
0
® Dielectric strength 0
*Quoliy assessed عدص GBPEW sovres, high-qualyy >
Review: C Dit etal J Bt Oowp Ded GOOD 9:0, 946
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Molecular and cellular
systems
۰ Enzymatic reactions (7/9 Hi-Qt* pub)
۰ Cultured cells (5/9 Hi-Qt pub)
® Basophil degranulation (8/11 Hi-at
pub)
*Qudliy assessed ری SBPEW svvres, high-qutiy >
OC Ott etd Oowp Ther Ded, OOO? WB 1608-90
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Animal systems
® One review in 1998 (no access)
© One review in immunology in 2006
Immunostimulation (16 pub)
Immunoregulation, inflammatory processes
(20 pub)
® No systematic review in this area
despite wide use and high number of
experiments
© Effect of thyroxin on frog ۹۷۹۳۹
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Human trials
© 134 RCT have been published
° 59 (44%) positive
°67 (50%) neutral (small effect)
°8 (6%) negative
© 23 systematic reviews
° 10 positive
58 non-conclusive
°5 little or no evidence
۳. Pisher Reseach ta Wewvenpaby: Oko weeds ٠" LOW 200006 H [2 |
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Human provings
or Human pathogenetic trials
® Only one review up to 1995
0
© More recent trials are of higher
quality
® Need a review of the recent
provings
© Need more trials LH] 2|
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Human provings
A successful example
دو امود 99۳0 ماه )و
00
Ooaspenilie sxepiows 2
1
و
ao
و
6
e
8
©
مه
&
Adapted from H. Méllinger
‘Homeopathic Drug Provings between historical and scientific demand’ LMHI 2408
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۳ 2 4 8 8
105 studies
15 Hi-Qt
studies
89 studies
32 Hi-Qt
studies
16 Hi-Qt
studies
8 (110) studies
Meta-analyses
Kleijnen eta/ 1991
Boissel eta/ 1996
Linde eta/1997*
Linde & Melchart
1998*
Cucherat etal 2000*
Shang etal 2005
ded in UK DARE
*Incli
(Database of Abstracts of Reviews of Effects)
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Shang eta/ 2005 Meta-
analysis
® Conclusions based on comparison of 8
homeopathy vs. 6 conventional medicine
trials, not 110 vs. 110
® Criteria for selection of 8 high-quality
trials were not given and no references
were given
® Does not conform with QUOROM
guidelines for systematic reviews
© Not classified as a systematic review by
UK DARE (Database of Abstracts of Reviews of Fffactc\
1۹
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Levels of evidence
+ Level | meta-analyses and/or systematic
reviews
Level Ila multiple controlled,
randomised experiments
Level IIb some controlled, randomised
experiments
Level Illa studies with multiple cohorts
Level Illb some cohort studies
Level IV opinion of experts LH] 2|
row Dickel vod Dassechved LOW 00
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Levels of evidence
® Material sciences lla+
(one systematic review)
© Molecular and cellular llat+
(one systematic review)
® Animals Illa / Ib
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Levels of evidence for human
trials
۱ | Overall (Meta analyses 5/6)
Allergic rhinitis, post-operative ileus,
I rheumatoid arthritis,
protection from toxic substances
Asthma, fibrosis, influenza,
۱۱ | muscular pain, otitis media, strains
ENT infections, side effect radiotherapy
Anxiety, ADHD, IBS, migraine,
طلا osteo-arthritis, PMS, Post-tonsillectiomy
analgesia,
nausea during chemotherapy, septicaemia
PO 1
۳ DEN
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Conclusions
° A lot of scientific evidence exists
® However, a lot of it is still of low quality
® Need more studies, esp. animal studies
® Many questions remain
=> Still need a lot of research
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صفحه 23:
Homeopathy Research
Institute
Aims:
°To perform and promote high-quality
scientific research in homeopathy
°To collate, clarify and disseminate
the existing scientific evidence in
homeopathy
صفحه 24:
Homeopathy Research
Institute
Scientific committee
Dr Alexander Tournier Pho
Clare Relton msc
Dr Robert Mathie ممم
Dr Elizabeth Thompson BAoxon MBBS MRCP
FFHom
Prof. Kate Thomas
Dr Lionel Milgrom ۵
Dr Mike Emmans Dean Php
Dr Nagin Lad ۵
Dr Natasa Peric-Concha Php
Dr Patti Bayliss mache FRCGP LH] 2|
صفحه 25:
Homeopathy Research
Institute
Current projects
Curated database of research articles
National survey of homeopathy practice
Scientific expertise for new research
projects
Homeopathy use in breast cancer patients
Membership scheme LH] 2|
صفحه 26:
Thank you
For more information:
alextournier@homeoinst.org
www.homeopathyresearchinstitute.
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