short tandom repeat

short tandom repeat

اسلاید 1: hort tandem repeatsProducer :Professor:

اسلاید 2: What is a short tandem repeats?also known as microsatellites (simple sequence repeats)a repetitive unit of 1–6 bperies with lengths of up to 100 nucleotidespolymorphicccounting for about 3% of the entire genomefound most in the noncoding regionsfound in prokaryotes and eukaryotescreated by Strand-slippage replication the stepwise mutation modelStably inherited on a human time scale (for most)

اسلاید 3: In genomethe highest density in chromosomeone STR occurs per 2,000 bp in the human genomeThe most common STRs in humans are A-rich units: A, AC, AAAN, AAN, and AGSTRs are classified into mono-, di-, tri-, tetra-, penta-, and hexanucleotide repeatsThe most common STRs in the human genome are dinucleotide repeatsWhile GC-rich trinucleotide expansions predominate in exonic regions, intronic repeats are composed of 3-6 nucleotide tandems and vary considerably in GC content