ناباروری مردان

ناباروری مردان

اسلاید 1: Free Powerpoint Templatesبسم الله الرحمن الرحیم

اسلاید 2: دکتر فاطمه نجات بخشمتخصص طب سنتی ایرانیعضو هیئت علمی دانشکده طب سنتی دانشگاه علوم پزشکی تهران

اسلاید 3: Treatment of male infertility with “Loboob”; an Iranian traditional medicament

اسلاید 4: Background:Infertility is defined as the inability to conceive after 12 or more months of regular intercourse without contraception.Infertility is a common condition with a prevalence of 10-15% in different societies.

اسلاید 5: Background:Sperm abnormalities are introduced as 20-47 % of infertility etiology. Idiopathic male subfertility is common (40-50%).

اسلاید 6: Background:many different treatments have been used include androgens, gonadotropins, and antiestrogens.androgen therapy in a study showed no significant improvement on semen parameters.

اسلاید 7: Background:Gonadotropins especially FSH have been conflicting, and Pure FSH has been 49% effective. GnRh, has lower success in comparison with gonadotropines. Antiestrogens like clomiphene can be useful only in 10-28% of cases.

اسلاید 8: Background:Unfortunately, up to now no definite medical treatments have been found to improve semen parameters or fertilization rate in men with idiopathic subfertility.

اسلاید 9: Background:Fertilization rate with assisted reproductive techniques (ART) which are very expensive, invasive, with both low conception rates per cycle and potential risks is about 7-40% in literatures.

اسلاید 10: Background:In Iranian traditional medicine, various treatment modalities for male infertility are available with “Loboob electuary” being one highly recommended.

اسلاید 11: Method:retrospective case series study“Loboob” effectiveness was evaluated on 13 infertile men suffering from idiopathic oligoasthenoteratospermia who were treated with 10g twice daily for at least 100 days.

اسلاید 12: Ingredients of Loboob electuary Name of drugsRatio (unit) Pistachio5Cocos nucifera5Corylus avellana L.5Pinus gerardiana 5Prunus species 10Sesamum orientale10Sugar10Myristica fragrans1Lepidium sativum1Piper elongatum1

اسلاید 13: Ingredients of Loboob electuary Name of drugsRatio (unit)Medicago sativa L.1Zingiber officinale2Piper cubeba2Boswellia carteri2Statice limonium L.3Centaurea behen3Alyssum minus L.6Skink1Urtica dioica L.1Honey140

اسلاید 14: Cases report:Meanwhile no other drugs except the Loboob electuary were given to the patients.All patients reported improvement of libido and erectile function, post electuary use.

اسلاید 15: Cases report:There was no report of drug intolerance. Wives of 11 cases (84/6%) became pregnant after a mean of 4/8±2 months (with a range of 3/3 and 10/6 months).

اسلاید 16: Cases report:All the 11 wives who became pregnant had a normal term pregnancy and gave birth to normal babies.

اسلاید 17: Cases report:In two other cases with very low sperm count (0.1×106/ml) , follow up tests after 4 months in one and 5 months in another didnt show any changes in sperm count.

اسلاید 18: Summary of patients’ information NoAge(yr)Infertility duration (yr)Sperm count (×106/ml)Sperm Motility (%)Sperm normal Morphology (%)Past historyPregnancy in wivesTx duration(month) 127517.65052Varicocele with surgery 3 years ago+10.62252127070-+3.33233157040-+5.3435101930181 Abortion 1 year ago+4.252640.54025-+46263114030-+3.67349183523Abortion 3 years ago+583768404IUI with pregnancy+4.4937104115IUI and IVF without any result+710372164020-+4.61132113405-+5123580.101IVF without any result-5132940.101--4

اسلاید 19: Discussion:it seems that Loboob electuary is effective in patients with sperm counts of  0/5×106/ml and in those with lower sperm counts, the treatment would not be useful.

اسلاید 20: Discussion:It might be that an extended duration of treatment can lead to different results and also having the semen analysis repeated during the treatment can yield evidence of its effects.

اسلاید 21: Discussion:Since successful pregnancy rate in healthy couples is 20% in a normal cycle, an average of 4/8 months for successful fertility with Loboob electuary would be very remarkable.

اسلاید 22: Discussion:Since spermatogenesis takes 70 days and sperm transfer from epididymis to ejaculatory duct lasts 12-21 days, it seems that Loboob electuary could resolve sperm abnormalities in the first 90 days required for sperm formation and transfer, and lead to successful fertilization.

اسلاید 23: Discussion:However, more studies should be made to clarify its efficiency on sperm count, motility and dysfunction.

اسلاید 24: تقدیم به شما