ریکاوری پس از سکته مغزی

ریکاوری پس از سکته مغزی

اسلاید 1: ریکاوری پس از سکته مغزی1

اسلاید 2: از فراگیر انتظار می رود در پایان این جلسه بتواند:مکانیسم های بهبودی پس از سکته مغزی را توضیح دهد. اصول نوروپلاستیسته در توانبخشی را توضیح دهد.بهبودی خودبخودی پس از سکته مغزی را توضیح دهد.تفاوت سیناپتوژنزیس رژنراتیو را از راکتیو شرح دهد.پیامد بیمار سکته مغزی که از مکانیسم های جبران استفاده می کند را توضیح دهد.2

اسلاید 3: neuropoplasticityThe exact mechanisms underlying this recovery process are not yet known, but several plausible mechanisms have been suggested. The first is synaptic plasticity, which occurs through the processes of axonal sprouting and synaptogenesis. These processes occur in the peri-infarct area of the brain, but can sometimes be seen in the contralateral hemisphere. The second mechanism is neurogenesis, which arises from endogenous neural stem cells in the subventricular zone and the dentate gyrus in the hippocampus. In this chapter, the suggested plausible mechanisms underlying the natural recovery process that occurs after stroke will be discussed.3

اسلاید 4: neuropoplasticityThe functional status of stroke patients spontaneously improves over 6 months after onset. More specifically, rapid recovery is achieved during the first month . From the patient’s perspective, rehabilitation is a process of regaining and relearning lost functions. Therefore, functional improvement, augmented by active rehabilitation overlaps with motor learning in terms of underlying mechanisms. Motor learning is associated with structural changes, such as axonal or dendritic growth along with new synapse formation and functional modulation including long-term potentiation or long-term depression, which may enhance or suppress synaptic activities. Together with the mechanisms above, cortical reorganization develops in the damaged brain, which plays an important role in recovery from acute stroke. Herein, we will elaborate on the functional recovery mechanisms after stroke.4

اسلاید 5: 5