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® Ebola 6
fever
© Crimean-Congo
Hemorrhagic Fever
© Hemorrhagic Fever
with Renal
Syndrome
© Argentina
Hemorrhagic Fever
© Kingella kinge
infection
~ Rift valley
~ Valley
© Rocky montain
5 Dengue
~ West nile
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Bunyaviridae
_ Largest family of mammal affecting viruses (250 viruses)
_ Arthropod- or rodent-borne vectors
’ Most are amplified in vertebrate hosts
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"Rift Valley Fever
Phlebovirus
Most spread by sandfly
or Ades species of
mosquitoes
Causes abortion in
livestock
Highly infectious by
aerosolized blood
Distribution follows
that of the host vectors »
Immunization of
livestock is the most
effective way to control
and prevent the disease
.م
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ی
19871998
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Secondary vectors include otrer mosauito
lerera such as Culee, and eatte, which can
Dass the urus to hursane and sna,
Produeng diseese. Human exposure fo veer
INestock blood and wssue can occtr during
Slaustering or Bring acities
he infected Aedes then foe on
uinersbiewwesteex, egonra rvs
‘implication ard an epizcoic-Epizocics
cause aberticn storms, with 90%
newborns snd 10.30% ماد ور
in adults. و
Rift Valley Fever (RVF) virus ecology
EptzvoUe-Epidemic eycle
میاه hgh rata and foodng اج موم
sees دک سر the ect بت
‘eeu rlanassive ewretgance of Aedes,
Bouin FF wens ntectd eds.
Enzootie Cycle
Local enzoote vansrissicn of RVF
‘occurs at low fvels mn natura dorm
periods of averaxe rafal The vrs
Eimamaned tough ansoveral
sronamissien from te female Aedes
moequvo to ner eggs a trough
[Sccassional ampliieation cycles
Stseepitie westocs
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Phlebovirus
Febrile disease in hum,
Targets the liver
Symptoms often includ}
Fever
Encephalitis
Retinal vasculitis (which may lead to blindness)
ee, 2"
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By
۳
P
~ Dengue
Fever =
Causes, Symptoms, Treatments, Prevention Tips
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+ Flavivirus are spherical
and 40- 60 mm in
diameter.
Genome — Positive sense,
single sense RNA,11kb in
size
Genome — RNA infectioug
Enveloped virus
Three structural
polypeptides two are
glycosylated
Replication in cytoplasm
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Febrile Phase 1
sudlden-onset fever <7 Critical Phase
hypotension
headache 1
1 pleural effusion
mouth and nose ۳ ascites
bleeding gastrointestinal
bleeding
1۱0500 ص270 ۱ ۱
00۱۴2۱6 ۱ 7 /
سات fi |) \, Recovery Phase
vomiting 1 i altered level of
} consciousness
rash seizures
0 itching
darthea4-}
۲۲۲ ۷۶
Aedes aegypti- mosquito
causing dengue
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Back Pain
Cae
Muscles
Aches
تا
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Symptoms — Dengue Fever
( Based on WHO )
* Fever, Chills ,
headache
° Myalgia
° Arthralgia
* Retro-orbital pain
* Deep bone pain —
“break bone fever”
* Rashes
* Positive Tourniquet
Test
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YATRA
Email: enquiry@medicyatra.com
What is the treatment for
dengue? ۱
Bray 10
treatment of a dengue infection.
«) Persons who think they have dengue
Enea teste Tir
8
۰ اعع
۱ emit S
۱ Wel ie
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INFOGRAPHICS
ELEMENTS 5 > 2
DENGUE FEVER ee
SYMPTOMS AND ۱
قح مرا
۳ 2 ۰
2 (17
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عمخ ۱۱
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SNe وک
ae
Okabe ~ (Worth carting
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Cause: FR. rickettsii
Infection occurs after tick bite
Incubation period: 1 week
Most serious form
More similar to typhus fever but the rash appears
earlier and is more prominent.
Initial symptoms: > Later signs and symptoms:
v Fever ¥ Maculopapular rash
y Nausea ! ۷7 اجه لوأاعماءم
¥ Emesis (vomiting) ¥ Abdominal pain
v Severe headache ¥ Joint pain
¥ Muscle pain v Forgetfulness
y¥ Lack
“e-'Y Parotitis
wv
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Rocky Mountain Spotted Fever
= Damage to blood vessels
Blood escapes, causing
low blood pressure,
insufficient oxygen and
nutrients to the body’s
organs
= ~5% of patients die even
with treatment
Non-itchy, spotted rash on the
» Life-threatening acute trunk and appendages, soles,
RMSF may involve palms
paralysis and secondary
infection by Clostridium = Can develop into petechiae
perfringens (subcutaneous hemorrhages)
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Rocky Mountain Spotted Fever
ساموت تا
Severe multiorgan dysfunction and
Me ey aici ccd ۱
Characteristic rash—days 2-6 of fever
101
Osc nem CCR Ree eek EN)
0
0 ا ل eee
۱۱۵ cee mT)
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* Nursing care
® Give tetracycline or doxycycline (except in children younger than 8 years)
* Provide supportive therapy for other symptoms (antipyretics, anti-inflammatory
medications and IV fluids)
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۱۳۳
إعناع] ۱/2۱2
What you need to.know
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هه
Coccidiodes:
Valley Fever
Whatis it? Where is it?
THE BIOLOGY OF COCCIDIOIDES
12
Wind
Centers for Disease Gontrol and Prevention
By Janet loehke and Kari Gelles, USA
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"Skin lesions from Valley Fever
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“Amphotericin
for Injection US ase
El
om wiRAVENOU!
INFUSION ORLY
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West Nile Fever
+ A flavivirus that is endemic in the Middle East, tropical
and subtropical Africa and southwest Asia.
+ Spread to the United States and Europe since 1997.
+ Lymphadenopathy, skin rash, transient meningeal
involvement and fatal encephalitis may occur in older
people (above 50 years)
In Cairo 70% of persons > 4 years have antibodies.
Birds are the reservoir of the virus.
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ود
3
osquto
WHATTYPES OFBIRDSCARRY 7220000007 a
WEST NILE VIRUS?
The virus has been
found in more than 150
bird species in North
America. Some species
may have no obvious
signs of illness when
infected. Others, such
as crows, blue jays,
magpies and ravens, get
sick more often and can
die.
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Can Manifest with Neurological illness
THE SYMPTOMS OF
NEUROLOGIC
ILLNESS CAN
INCLUDE
HEADACHE, HIGH
FEVER, NECK
STIFFNESS, DISORIE
NTATION, COMA, TR
EMORS, SEIZURES,
OR PARALYSIS.
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TESTS
Plaque-reduction
neutralization tests
(PRNTs) performed in
reference laboratories,
including some state
public health |
laboratories and CDC,
|
REFERENCE LABORATORY
can help determine the
specific infecting
flavivirus.
OTHER TESTING FOR WNV
DISEASE
Viral cultures and tests to
detect viral RNA
(e.g. reverse transcriptase-
polymerase chain reaction
[RT-PCR}) can be
performed on
Serum, CSF, and tissue
specimens that are
collected early in the
course of ilness and, it
results are positive, can
confirm an infection,
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<< سح 1 PREVENTION OF WEST NILE FEVER
٠ 18أم095 59 30]
eee oy
16 00
000 ۷/۵۵
۷ 9۷9 وانلا
SCC!
9 91006
needed to protect
۷
Use insect repellents when
you go outdoors.
Repellents containing
DEET, picaridin, 183535, 0ه
some oll of lemon
eucalyptus and para-
‘menthane-diol products
provide longer-lasting
protection. To optimize
safety and
effectiveness, repellents
should be used according
to the label instructions
33
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Crimean-Congo Hemorrhagic
- Fever
Nairovirus ۳
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STATS
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Crimean-Congo Hemorrhagic —
Fever
Nairovirus ۳ se
Transmitted by ticks ۴8 ۳
Appears in the Middle k 9 آ
East and Africa «۹
Targets the liver and
vascular endothelium
Symptoms include:
Headache
Pain in limbs
Often bleeding from 7 i
many orifices
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solid surface, such as the
inner surface of a test
snes tbe;
* a preparation of the same
antibodies coupled to an
‘enzyme. This is one (e.g.,
serene Prgalectosidase) that
Yesemnya? oles produces a colored
0 product from a colorless
substrate.
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Vectors
Transmitted via 52002 ۱
aerosolized rodent urine, متا
feces, and saliva
, Deer mouse (Peromyscus
maniculatus)
Cotton rat (Sigmodon
hispidus)
بر White-footed mouse
(Peromyscus leucopus)
. Striped field mours
(Apodemus agrarius)
Bank vole (Clethrionomy:
glareolus)
— Rat (Rathic)
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iver and vascular enothelium are targete
yymptoms include:
+ Hemorrhage
a
Acute renal failure aS a
Fever
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موس وه ۳
Dee
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۱ Ebola
Virus
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Ebola outbreak 5۳ > ۳ ۲ ی
An outbreak of the deadly ire, GUINEA nes
Ebsia virus has 801/54 at loast صمي 1
25 ج هه مرت ره مر مود
= مج منت ری ره تحت هد
ت and kills botweer 25 and Atiantia a
90 percent of Victims: tnere سم 2 Se و
Ebola virus" typical path through a human being
اي
First 7 - 5
symptoms
COO Coo
Day 7-9 Day 10 Day 11
Headache. Sudden high Bruising. brain
fatigue. fever. fever. vo! 9 damage.
muscle blood. passive bleeding from
soreness behavior nose. mouth.
©2014 mer ‘eyes. anus
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Ahemorthagic
rash appears
over entire
Symptoms of
Ebola
Headache < f
Red Eyes 2 7 1 Pharynx and lungs
ید - Hiccups
Systemic - Sore throat
- Fever / - Difficulty breathing
- Lack of appetite - Difficulty swallowing
- Internal bleeding
Chest pain
2 5
2 72
- Aches + / Stomach
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۹ ) ۲ ۱ 8
۰
LY Gy و
Headache ۰ ۵ Internal Vomiting Diarrhea
Fatigue Bleeding Throat
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* the antibodies fixed to a
"2 sold surface, such as the
inner surface of a test
come tube;
* a preparation of the same
antibodies coupled to an
enzyme. This is one (e.9,,
tosidase) that
produces a colored
product from a colorless
substrate
=
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A rgentine
emorrhagic ا
F ever
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Background
Kingella kingae: ان
Major cause of osteoarticular infections ( /
children under 4 years.
Belongs to the normal oropt
‘ic carriers)
Colonization of the
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Mol® G + C of DNA
Pi see ei
—
+
+
+
+
75
4
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Bacterial Endocarditis
Mitral valve
Aortic valve
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KINGELLA KINGAE در
۶ 000۱۵201105 Gram —
x Orofaringe humana
x Necesidades exigentes de crecimiento
%* 3 dias de incubacion _
ingots igo
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Ciprofloxacin
axapharm